Clinical trials of penicillamine in Indian childhood cirrhosis.

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Clinical trials of penicillamine in Indian childhood cirrhosis.

The outcome in 15 children with advanced Indian childhood cirrhosis (ICC) treated with penicillamine 20 mg/kg/day was not significantly different from that in untreated children. Among children admitted to a further double blind trial who had ICC but who had not yet developed jaundice or ascites 10 treated with penicillamine and 10 treated with penicillamine plus prednisolone had a significantl...

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Indian Childhood Cirrhosis: Case Report and Pediatric Diagnostic Challenges

Introduction: Indian childhood cirrhosis is a chronic liver disease usually seen in paediatric age group and is unique to the Indian subcontinent. The definitive causative factor for the disease is not found till now but excess copper ingestion has been associated with it.Case presentation: An Indian origin one and half year old premorbidly normal male child presented with history of gradual di...

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Long term survival in Indian childhood cirrhosis treated with D-penicillamine.

Indian childhood cirrhosis (ICC) is an almost uniformly fatal disease whose outcome may be modified with penicillamine if given at a sufficiently early stage. Twenty nine children with ICC seen in Pune, India, in 1980-7, who had survived at least five years from onset of penicillamine treatment, were reviewed aged 6.3 to 13 years. They were assessed clinically, biochemically, histologically, an...

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Indian childhood cirrhosis.

Neviasa JS. Adhesive capsulitis of the shoulder. A study of the pathological findings in periarthritis of the shoulder. J Bone J'oint Surg 1945 ;27 :211-22. 2 Bruckner FE, Nye CJS. A prospective study of adhesive capsulitis of the shoulder ("frozen shoulder") in a high risk population. Q 7 Med 1981; 198:191-204. 3Wright V, Haq AMMM. Periarthritis of the shoulder. II. Radiological features. Ann ...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1987

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.62.11.1118